I'd rather they keep it a bit more gritty and leave the stupid stuff to Saints Row, can't see it being the case though if it is in LA.
There's a middle ground to be struck, I think. I'm fairly sure they could have a lighter-hearted GTA without tipping into Saint's Row ridiculous.
I'd like to see more properties to buy and businesses to run. As much as I enjoyed Lost & Damned, it seemed a bit daft that I had oodles of cash and yet continued to sleep on an old mattress. At least give me the opportunity to buy a new mattress and maybe a nice comfy pillow.
The drug dealing in Chinatown Wars was great - more stuff like that please.
Actually, that kind of made sense to me. Niko may have had cash, but not the means (or connections) to launder it. Though I didn't play the episodes, so I don't know about Lost and Damned or TBOGT.